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FOLATE FOR DEPRESSION

This systematic review was undertaken to see if giving folate to people with depressive disorders reduced their depressive symptoms. Three randomized trials were identified, involving a total of 247 people. In all three trials, folate was well tolerated. In two of these trials, folate was added to other antidepressant drug treatment and there was limited … Continue reading

LONG-TERM NON-PHAMACHOLOGICAL WEIGHT LOSS INTERVENTIONS FOR ADULTS WITH T2DM

Most persons with type 2 diabetes are overweight, and the health of these persons can be improved with weight loss. Weight loss is very difficult to achieve in the long-term, however, particularly among persons with diabetes. This systematic review of diet, physical activity, and behavioral interventions for weight loss, revealed a decrease in weight of … Continue reading

METFORMIN MONOTHERAPY FOR T2DM

Our review confirm that tight glycaemia control with metformin monotherapy is one of the main therapeutic options for type 2 diabetes in patients with overweight or obesity, since it may prevent some events of macrovascular and microvascular complications, and mortality. With the exception of more benefit achieved in overweight and obese participants on metformin, there … Continue reading

OMEGA 3 PUFA FOR T2DM

People with type 2 diabetes are known to be at increased risk of cardiovascular disease (such as heart attack or stroke). Type 2 diabetes mellitus is the fourth leading cause of death in developed countries with a two fold excess mortality and a two to four fold increased risk of coronary heart disease and stroke. … Continue reading

THERE IS NOT ENOUGH EVIDENCE TO SAY THAT PEOPLE SHOULD STOP TAKING OMEGA 3

Abstract Background It has been suggested that omega 3 (W3, n-3 or omega-3) fats from oily fish and plants are beneficial to health. Objectives To assess whether dietary or supplemental omega 3 fatty acids alter total mortality, cardiovascular events or cancers using both RCT and cohort studies. Search methods Five databases including CENTRAL, MEDLINE and … Continue reading

RELAXATION FOR HYPERTENSION

The World Health Organisation estimates that high blood pressure leads to over 7 million deaths each year, about 13% of the total deaths worldwide. If people lower their blood pressure, they are less likely to die or to have heart attacks and strokes. If someone’s blood pressure is only slightly too high, they may prefer … Continue reading

ORAL MAGNESIUM SUPPLEMENTATION FOR HYPERTENSION IN ADULTS

This review examined whether taking magnesium supplements could be recommended for treating adults with high blood pressure from no known cause. It reviewed 12 trials enrolling 545 people, which compared magnesium supplementation with a dummy drug (placebo) or no treatment, and measured blood pressure 8 weeks to 6 months later. The results of trials varied … Continue reading

CALCIUM SUPPLEMENTATION FOR MANAGEMENT OF PRIMARY HYPERTENSION IN ADULTS

This review did not find robust evidence that oral calcium supplementation reduces high blood pressure in adults. It reviewed 13 trials enrolling 485 people, which compared calcium supplementation with placebo or no treatment, and measured blood pressure 8 to 15 weeks later. On average, people receiving extra calcium achieved slightly lower systolic blood pressure at … Continue reading

COMBINED CALCIUM, MAGNESIUM AND POTASSIUM SUPPLEMENTATION FOR MANAGEMENT OF PRIMARY HYPERTENSION IN ADULTS

Elevated blood pressure (BP) or hypertension can lead to cardiovascular disease, stroke and renal disease. Epidemiological studies suggest that changing the dietary levels of calcium, potassium, magnesium or sodium can affect BP in some people. This systematic review focuses on the effects of concurrently attempting to change any combination of calcium, magnesium, or potassium levels … Continue reading

WHOLE GRAIN FOODS FOR THE PREVENTION OF TYPE 2 DIABETES MELLITUS

Food products derived from cereal grains as wheat, rice, corn, rye, oat, and barley constitute a major part of the daily diet in many countries. In refined-grain products, the bran and germ of the grain, which contain the major amount of nutrients and dietary fibre, have been removed and only the starchy inner part of … Continue reading