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Resveratrol: potential as anticancer agent.

Feik School of Pharmacy, University of the Incarnate Word, San Antonio, Texas 78209, USA. Abstract BACKGROUND: Cancer is one of the leading causes of deaths in the world. Current chemotherapeutic agents are associated with serious side effects in patients therefore researchers are trying to find an alternative agent that is effective against cancer as well … Continue reading

The journey of resveratrol from yeast to human.

Top Institute Food and Nutrition (TIFN), Wageningen, The Netherlands. Abstract The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given … Continue reading

ANTIOXIDANT SUPPLEMENTS FOR PREVENTION OF MORTALITY IN HEALTHY PARTICIPANTS AND PATIENTS WITH VARIOUS DISEASES

Previous research on animal and physiological models suggests that antioxidant supplements have beneficial effects that may prolong life. Some observational studies also suggest that antioxidant supplements may prolong life, whereas other observational studies demonstrate neutral or harmful effects. Our Cochrane review from 2008 demonstrated that antioxidant supplements seem to increase mortality. This review is now … Continue reading

Sorting out ‘sleep hygiene’

Lifestyle, particularly your sleeping habits, have a big impact on your quality of sleep. Addressing so-called ‘sleep hygiene’ should be the first step in any treatment of insomnia. Sleep hygiene is a list of lifestyle dos and don’ts. It has proved to be effective in stopping insomnia from getting worse, and making it easier to benefit … Continue reading

Sirtuins as regulators of metabolism and healthspan.

Laboratory for Integrative and Systems Physiology, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. Abstract Since the beginning of the century, the mammalian sirtuin protein family (comprising SIRT1-SIRT7) has received much attention for its regulatory role, mainly in metabolism and ageing. Sirtuins act in different cellular compartments: they deacetylate histones and several transcriptional regulators in the … Continue reading

GNC Sued Over Dangerous Exercise Supplement

GNC is being sued in a class action consumer fraudlawsuit by a Southern California woman who claims that the company made false claims about an exercise aid supplement, C4 Extreme, sold by the retailer that contains the controversial substance known as DMAA. According to the North County Times, Lynette Bates is suing GNC, Woodbolt International and Cellucor Sports … Continue reading