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Prediabetes: a high-risk state for diabetes developmen

Department of Epidemiology and Public Health, University College London, London, UK. a.tabak@ucl.ac.uk Abstract Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined by glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5-10% of people per year with prediabetes will progress to diabetes, with the same proportion converting back … Continue reading

ANTIOXIDANT VITAMINS AND MINERAL SUPPLEMENTS TO PREVENT THE DEVELOPMENT OF AMD

Age-related macular degeneration (AMD) is a condition affecting the central area of the retina (back of the eye). The retina can deteriorate with age and some people get lesions that can lead to loss of central vision. Some studies have suggested that people who eat a diet rich in antioxidant vitamins (carotenoids, vitamins C and … Continue reading

FISH OILS FOR THE PREVENTION OF DEMENTIA IN OLDER PEOPLE

Dementia is a progressive illness which mainly affects older people. Previous research from observational studies has suggested that increased consumption of fish oils rich in omega-3 long-chain polyunsaturated fatty acids (omega-3 PUFA) may reduce the chance of developing dementia, while other studies show no effect. Oily fish, such as salmon, mackerel, herring and sardinesĀ are a … Continue reading

Are sirtuins viable targets for improving healthspan and lifespan?

Department of Physiology and Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. baur@mail.med.upenn.edu Abstract Although the increased lifespan of our populations illustrates the success of modern medicine, the risk of developing many diseases increases exponentially with old age. Caloric restriction is known to retard ageing and … Continue reading